Mike,
I wish peace to you and your family as you deal with this difficult situation. I can relate--a close family member with a long history of heart medication polypharmacy and valve disease (from childhood rheumatic fever) started to develop edema, coughing, and fatigue a few years ago. These are TEXTBOOK symptoms of heart failure. He went to his family physician, who felt he had some kind of cold or flu, and prescribed an antibiotic. A week later, he collapsed and ended up in the ICU for 2 weeks, on a ventilator for most of it. It took the docs several days to realize he was in heart failure. I was vocal about my concerns right away, but because he and his wife were diehard always-trust-the-doctor people, they didn't question anything their docs said. And I even presented them with many studies indicating that statins can actually cause heart failure. Considering his valve issues, you'd think the docs would have explored another way of lowering his cholesterol without the statins.
Anyway, I completely agree with all those in this thread discussing the importance of taking responsibility for your own health, or for an advocate to represent an elderly patient. Polypharmacy and an exploding elderly population is becoming a larger and larger issue that we cannot ignore.
Over the past 10 years, I've developed and edited 6 nursing pharmacology textbooks for several large textbook publishers. This experience has opened my eyes to the negative impact of drug therapy...these books are essentially compendiums of managing side effects, yet physicians and nurses are taught that drug therapy is the basis of "health" care.
There may still be safe ways to improve your grandfather's quality of life and restore his dignity. For example,
I wonder if a gentle detoxification program might help to clear out the toxins created by the narcotic, and improve brain function. Another thought is CoQ10 and fish oils.
But do some research...If you want to stick with researching possible solutions from only peer-reviewed journals, PubMed is a great resource:
PubMed Home
You won't be able to read the entire journal article, but the abstract gives you a good synopsis to spur further research on the 'net.
Another thought is to find a doctor who specializes in treating the older adult (gerontologist)...they should be specialists in polypharmacy, and may have a good solution for handling the current situation. You can search for a more holistically oriented physician on various sites, too...here's one that I use a lot:
ACAM Homepage - American College for Advancement in Medicine
Sending positive thoughts your way for peace and health to you and your grandfather,
ElenaMaria