We moved from Denver to Port St Joe with 300 lbs of mastiff (and an ancient cat). The drive (Volvo wagon) took something like 3 days, maybe 4. We had their dog and kitty beds, food bowls etc. The only difficult part was when we discovered that Rosie was terrified of elevators. (We did the stairs instead.)
We stayed in dog-friendly hotels. (Dogfriendly.com or something like that.)
Just recently, we took Elwood to Tallahassee when we took the kid back to school. Taking a dog on vacation is certainly doable. Our next goal is figuring out how to take Elwood out on the boat, he has never done this before (we're new to it ourselves.) ;-)
We stayed in dog-friendly hotels. (Dogfriendly.com or something like that.)
Just recently, we took Elwood to Tallahassee when we took the kid back to school. Taking a dog on vacation is certainly doable. Our next goal is figuring out how to take Elwood out on the boat, he has never done this before (we're new to it ourselves.) ;-)

all over the windows and window sill.